Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

MAB2008

Sigma-Aldrich

Anti-Integrin β3 Antibody, clone SAP

clone SAP, Chemicon®, from mouse

Sinonimo/i:

CD61

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

SAP, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

Isotipo

IgG1κ

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... ITGB3(3690)

Specificità

Monoclonal antibody MAB2008 is specific for the beta-3 subunit of the vitronectin receptor (VNR)J, which is expressed on endothelial cells, platelets, melanoma, and glioma cells. The antibody is of high affinity.

Immunogeno

Membranes of freshly isolated human platelets.

Applicazioni

Detect Integrin β3 using this Anti-Integrin β3 Antibody, clone SAP validated for use in WB, IH, IH(P).
Immunohistochemistry (frozen and fixed tissue sections) including paraffin embedded sections. {See Van Belle et al 1999, original paper detailing the use in human, paraffin tissues}

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10333228.

Western blot: recognizes ~115kDa band in reduced

Optimal working dilutions must be determined by end user.

Stato fisico

Format: Purified
Purified immunoglobulin. Liquid at 1 mg/mL in 0.02M phosphate buffer, 0.25M sodium chloride, pH 7.6, containing 0.1% sodium azide as a preservative.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Raccomandato

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Upregulation and secretion of kallikrein-related peptidase 6 (KLK6) in gastric cancer.
Jin Ju Kim,Jong-Tae Kim,Hyo Ran Yoon,Min Ah Kang,Joo Heon Kim,Young-Ha Lee,Jae Wha Kim et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine null
G Gruber et al.
British journal of cancer, 92(1), 41-46 (2004-12-15)
Integrins are cell-surface receptors, which mediate cell-to-cell and cell-to-extracellular matrix adhesion. Besides playing an important role in tumour angiogenesis, beta3-integrin is also expressed in several types of epithelial cancer cells. It was the purpose of the present study to evaluate
Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells.
Yan-Xi Sun,Ming Fang,Jianhua Wang,Carlton R Cooper,Kenneth J Pienta,Russell S Taichman
Prostate null
P A Van Belle et al.
Human pathology, 30(5), 562-567 (1999-05-20)
The expression of the beta3 integrin subunit was investigated in 130 fixed, paraffin-embedded specimens of human melanomas and nevi using two different monoclonal antibodies. Expression was not observed in melanocytes and was absent or low in most nevi. In primary
Renée DuQuesnay et al.
Fertility and sterility, 91(2), 489-499 (2008-03-21)
To characterize possible endometrial defects in infertile women with isolated PCO morphology. Prospective study. An academic hospital with an IVF unit. Women with primary unexplained infertility and isolated PCO, fertile women, and women with infertility secondary to male factor. Thirty-one

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.