MAB1645

Anti-Dystrophin Antibody

CHEMICON^®, mouse monoclonal, 1808

• Sinonimo/i: Anti-BMD, Anti-CMD3B, Anti-DXS142, Anti-DXS164, Anti-DXS206, Anti-DXS230, Anti-DXS239, Anti-DXS268, Anti-DXS269, Anti-DXS270, Anti-DXS272, Anti-MRX85
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• product name: Anti-Dystrophin Antibody, clone 1808, clone 1808, Chemicon^®, from mouse
• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: 1808, monoclonal
• Reattività contro le specie: chicken, mouse, rat, human
• Produttore/marchio commerciale: Chemicon^®
• tecniche: immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1
• N° accesso NCBI: NM_000109.2; NM_004006.1; NM_004007.1; NM_004009.2; NM_004010.2; NM_004011.2; NM_004012.2; NM_004013.1; NM_004014.1; NM_004015.1; NM_004016.1; NM_004017.1; NM_004018.1; NM_004019.2; NM_004020.1; NM_004021.1; NM_004022.1; NM_004023.1
• N° accesso UniProt: P11532
• Condizioni di spedizione: dry ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... DMD(1756)

Descrizione

Specificità

By Western blot MAB1645 recognizes a single protein having a relative molecular weight of 300 kD. Reacts to mammalian skeletal muscle dystrophin. Shows no staining of mdx mouse muscle. Labels normal human muscle but not Duchenne muscle.

STAINING PATTERN:

On cryostat sections of normal mouse diaphragm MAB1645 gives strong immunofluorescence staining of the entire sarcolemma, with particularly strong staining of neuromuscular junctions.

SPECIES REACTIVITY:

Labels skeletal muscle from rat, chicken and Xenopus laevis. Labels cardiac muscle from rat and normal, but not mdx, mouse. Also labels smooth muscle from chicken gizzard.

Immunogeno

Peripheral membrane proteins extracted from Torpedo postsynaptic membranes.

Applicazioni

Anti-Dystrophin Antibody, clone 1808 detects level of Dystrophin & has been published & validated for use in WB, IH.

Western blot

Immunohistochemistry

Optimal working dilutions must be determined by the end user.

Stato fisico

Format: Purified

Liquid in 0.02 M phosphate buffer (pH 7.6), 250 mM NaCl with 0.1% sodium azide.

Stoccaggio e stabilità

Maintain at -20ºC for up to 12 months in convenient aliquots. Avoid repeated freeze/thaw cycles.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable