MAB10404

Anti-Ghrelin Antibody, clone 1ML-1D7

ascites fluid, clone 1ML-1D7, from mouse

• Sinonimo/i: ghrelin/obestatin prepropeptide1, ghrelin/obestatin2, ghrelin, growth hormone secretagogue receptor ligand1, obestatin1, ghrelin/obestatin preprohormone, Motilin-related peptide2, ghrelin1, M46 protein3, Growth hormone secretagogue
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: ascites fluid
• Tipo di anticorpo: primary antibodies
• Clone: 1ML-1D7, monoclonal
• Reattività contro le specie: mouse, human
• tecniche: immunocytochemistry: suitable; western blot: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_057446.1
• N° accesso UniProt: Q9UBU3
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... GHRL(51738)

Descrizione

Descrizione generale

Ghrelin is a 28 amino acids peptide with an essential n-octonayl modification at Serine 3. This peptide hormone is known as an endogenous ligand for the growth hormone secretagogue receptor and shares sequence similarity with the peptide hormone Motilin. Ghrelin displays pleotropic actions including growth hormone secretion, feeding behaviour and gastrointestinal motility. It is predominantly produced by enteroendocrine cells from the gastrointestinal tract, but has been shown to play a significant role in neurotrophy, particularly in the hippocampus, and appears to be essential for cognitive adaptation to changing environments and the process of learning.

Specificità

This antibody recognizes Ghrelin at the N-terminus.

Immunogeno

Linear Peptide corresponding to the N-terminus of human Ghrelin.

Applicazioni

Detect Ghrelin using this Anti-Ghrelin Antibody, clone 1ML-1D7 validated for use in WB & IC.

Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected Ghrelin in A431 cells.

Qualità

Evaluated by Western Blot in mouse stomach tissue lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Ghrelin in 10 µg of mouse stomach tissue lysate.

Descrizione del bersaglio

13 kDa calculated and observed

Risultati analitici

Control
Mouse stomach tissue lysate

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1