GF050

Leptin, mouse

Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice & appears to be involved in appetite control.

• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Saggio: >95% (SDS-PAGE and HPLC)
• Produttore/marchio commerciale: Chemicon^®
• tecniche: cell culture | mammalian: suitable
• input: sample type mesenchymal stem cell(s)
• N° accesso UniProt: P41159; P41160
• Condizioni di spedizione: wet ice

Descrizione

Descrizione generale

Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and appears to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body′s fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Mouse leptin is a 16 kDa protein containing 147 amino acid residues.

Product Source: E.coli

Stato fisico

Lyophilized from 0.1% TFA, no preservatives.

Stoccaggio e stabilità

The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C for up to 12 months from date of receipt. After a quick spin, reconstitute the mouse leptin in sterile distilled water to a concentration of 1.0-5.0 mg/mL. After reconstitution maintain at -20°C in undiluted aliquots for up to six months.

Risultati analitici

Specific Activity: GF050 has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 μg leptin/gm of body weight for 14 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed compared to saline-treated controls.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319
• Consigli di prudenza: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2
• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable