FCMAB255F

Milli-Mark^® Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1

clone TC11-18H10.1, Milli-Mark^®, from rat

• Sinonimo/i: Cytotoxic T-lymphocyte-associated antigen 8
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rat
• Coniugato: FITC conjugate
• Forma dell’anticorpo: affinity purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: TC11-18H10.1, monoclonal
• Reattività contro le specie: mouse
• Produttore/marchio commerciale: Milli-Mark^®
• tecniche: flow cytometry: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_034682
• N° accesso UniProt: Q62386
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Il17A(16171)

Descrizione

Descrizione generale

IL17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL1beta, IL6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL17are significantly increased and may contribute to bone destruction.

Specificità

Antibody recognizes Interleukin-17A.

Immunogeno

Recombinant protein corresponding to mouse Il17a

Applicazioni

Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1 detects level of Mouse IL-17 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunological Signaling

Qualità

Evaluated by flow cytometry using stimulated EL-4 cells

Descrizione del bersaglio

17 kDa Calculated

Stato fisico

Antigen Affinity Purified

Purified rat monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Stoccaggio e stabilità

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Risultati analitici

Control
PMA and Ionomycin stimulated EL-4 cells.

Note legali

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable