ABS562

Anti-CH25H Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human
• tecniche: western blot: suitable
• N° accesso NCBI: NP_003947
• N° accesso UniProt: O95992
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... CH25H(9023)

Descrizione

Descrizione generale

CH25H , also known as Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH, and encoded by the gene name CH25H, is a member of the sterol desaturase family. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol, which in turn leads to repression of the cholesterol biosynthetic enzymes. Recent studies have shown that CH25H may play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. Other studies have also indicated that in testis, production of 25-hydroxycholesterol may play a role in Leydig cell differentiation.

Immunogeno

Epitope: Near N-terminus

KLH-conjugated linear peptide corresponding to human CH25H near the N-terminus.

Applicazioni

Research Category
Signaling

Research Sub Category
Signaling Neuroscience

This Anti-CH25H antibody is validated for use in Western Blotting for the detection of CH25H.

Qualità

Evaluated by Western Blotting in THP-1 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected CH25H in 10 µg of THP-1 cell lysate.

Descrizione del bersaglio

~32 kDa observed

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Altre note

Concentration: Please refer to lot specific datasheet.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable