ABN207

Anti-DBN1 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Drebrin, Developmentally-regulated brain protein, DBN1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse, horse, human, rat
• Reattività contro le specie (prevista in base all’omologia): bovine (based on 100% sequence homology), equine (based on 100% sequence homology)
• tecniche: immunohistochemistry: suitable (paraffin); western blot: suitable
• N° accesso NCBI: NP_004386
• N° accesso UniProt: Q16643
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... DBN1(1627)

Descrizione

Descrizione generale

Drebrin (Developmentally-regulated brain protein) is also known by the gene name DBN1. Drebrins are found in the cytoplasm of brain neurons as well as tissues including heart, placenta skeletal muscle kidney and pancreas. Debrin binds F-actin and is involved in the mechanisms of development, cell migration, neuronal processes and dendrite plasticity.

Immunogeno

KLH-conjugated linear peptide corresponding to human DBN1.

Applicazioni

Immunohistochemistry Analysis: A 1:4,000 dilution from a representative lot detected DBN1 in human cerebellum and rat midbrain tissues.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

This DBN1 antibody is validated for use in WB & IHC for the detection of the DBN1 protein.

Qualità

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected DBN1 in 10 µg of mouse brain tissue lysate.

Descrizione del bersaglio

~110 kDa observed. The calculated molecular weight is 71 kDa, however DBN1 has been shown as a ~110 kDa band in western blotting (Maezawa, I., et al. (2006). Novus Biologicals. 1-2).

Linkage

Replaces: AB15288

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Mouse brain tissue lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable