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Documenti fondamentali

ABE571

Sigma-Aldrich

Anti-SOX9 Antibody

rabbit polyclonal

Sinonimo/i:

Transcription factor SOX-9

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Nome del prodotto

Anti-SOX9 Antibody, from rabbit, purified by affinity chromatography

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

mouse

Reattività contro le specie (prevista in base all’omologia)

rat (based on 100% sequence homology), human (based on 100% sequence homology)

tecniche

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... SOX9(6662)

Descrizione generale

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Immunogeno

Linear peptide corresponding to the C-terminus of human SOX9.

Applicazioni

Anti-SOX9 Antibody is a highly specific rabbit polyclonal antibody, that targets SOX9 & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected SOX9 in K14 mouse backskin tissue (Nowak, J. A., et al. (2008). Cell Stem Cell. 3(1):33-43.).

Immunofluorescence Analysis: A representative lot from an independent laboratory detected SOX9 in mouse Label Retaining cells, and developing epithelial skin and hair follicle cells (Nowak, J. A., et al. (2008). Cell Stem Cell. 3(1):33-43.).
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Qualità

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected SOX9 in 10 µg of NIH/3T3 cell lysate.

Descrizione del bersaglio

~63 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

Stato fisico

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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