ABD101

Anti-ESRRB Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Steroid hormone receptor ERR2, ERR beta-2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.75

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse
• Reattività contro le specie (prevista in base all’omologia): human (based on 100% sequence homology)
• tecniche: immunocytochemistry: suitable; western blot: suitable
• N° accesso NCBI: NP_004443
• N° accesso UniProt: O95718
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ESRRB(2103)

Descrizione

Descrizione generale

The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.

Immunogeno

KLH-conjugated linear peptide corresponding to Amino acids 376-388 of Human ESRRB protein.

Applicazioni

Immunocytochemical Analysis: 1:50 dilution of this antibody detected ESRRB in a mouse embryonic stem cells.

This Anti-ESRRB Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of ESRRB.

Qualità

Evaluated by Western Blot in a mouse brain E16 lysate. Western Blot Analysis: 1μg/ml of this antibody detected ESRRB in a mouse brain E16 lysate. Uncharacterized bands may be observed in some cell lysates with longer exposure times.

Descrizione del bersaglio

~56 kDa observed

Altre note

Concentration: Please refer to lot specific datasheet.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable