AB9680
Anti-GABA A Receptor β 1 Antibody
Chemicon®, from rabbit
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
rabbit
Livello qualitativo
Forma dell’anticorpo
affinity purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Purificato mediante
affinity chromatography
Reattività contro le specie
human, rat, mouse
Produttore/marchio commerciale
Chemicon®
tecniche
western blot: suitable
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... GABRB1(2560)
Specificità
GABAA Receptor beta 1 subunit. The antibody recognizes a protein of ~55 kDa corresponding to GABAA Receptor beta 1 subunit in lysates from rat cerebellum and cortex.
Immunogeno
Fusion protein from the Cytosolic loop of rat the GABAA Receptor beta 1 subunit.
Applicazioni
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
This Anti-GABA A Receptor β 1 Antibody is validated for use in WB for the detection of GABA A Receptor β 1.
Western blot: 1:1,000.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Linkage
Replaces: AB5451
Stato fisico
Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
Stoccaggio e stabilità
Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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R W Olsen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 4(5), 1469-1480 (1990-03-01)
The major type of receptor for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), called the GABAA receptor, is a member of a gene superfamily of ligand-gated ion channels. This receptor is a hetero-oligomeric protein composed of several distinct polypeptide types (alpha
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit.
Ogris W, et al.
Biochemical Pharmacology, 68, 1621-1629 (2004)
Angelika Pöltl et al.
Journal of neurochemistry, 87(6), 1444-1455 (2004-01-10)
In cerebellum, 13 different GABA(A) receptor subunits are expressed. The number of different receptor subtypes formed in this tissue, their subunit composition and their quantitative importance so far has not been determined. In the present study, immunodepletion by immunoaffinity chromatography
A K Mehta et al.
Brain research. Molecular brain research, 67(1), 194-199 (1999-04-02)
The anti-alpha1 antibody elicited higher immunoprecipitation (%) values of the [3H]flunitrazepam and [3H]muscimol binding activity in the rat cerebellum vs. cerebral cortex, whereas immunoprecipitation values for [3H]Ro 15-4513 and [3H]zolpidem were comparable in these brain regions. Chronic ethanol administration neither
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Suicide is a major public health concern; nevertheless, its neurobiology remains unknown. An area of interest in suicide research is the dorsolateral prefrontal cortex (DLPFC). We aimed to identify altered proteins and potential biological pathways in the DLPFC of individuals
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