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Merck
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Documenti fondamentali

AB3349

Sigma-Aldrich

Anti-PRMT5 Antibody, CT

Chemicon®, from rabbit

Sinonimo/i:

Anti-HRMT1L5, Anti-HSL7, Anti-IBP72, Anti-JBP1, Anti-SKB1, Anti-SKB1Hs

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
western blot: suitable

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... PRMT5(10419)

Specificità

Reacts with PRMT5.

Immunogeno

Epitope: C-terminus
Synthetic peptide from C-terminus of human PRMT5.

Applicazioni

Anti-PRMT5 Antibody, C-terminus is a high quality Rabbit Polyclonal Antibody for the detection of PRMT5 & has been validated in ELISA & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Western Blot: 1:100-1:500. Reacts with a band of approximately 70 kDa on whole HL60 cell lysate. Additional bands may be present depending on sample used.

ELISA (direct): 1:1,000

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: MABE551

Stato fisico

Format: Purified
Purified immunoglobulin in PBS containing 0.09% sodium azide.

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Risultati analitici

Control
POSITIVE CONTROL: HL60 cell lysates.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Arginine methylation of a mitochondrial guide RNA binding protein from Trypanosoma brucei.
Pelletier, M, et al.
Molecular and Biochemical Parasitology, 118, 49-59 (2001)
Establishment of a versatile seminoma model indicates cellular plasticity of germ cell tumor cells.
Daniel Nettersheim,Birgit Westernstroer,Natalie Haas,Anke Leinhaas,Oliver Brustle et al.
Genes Chromosomes Cancer null
A Frankel et al.
The Journal of biological chemistry, 275(42), 32974-32982 (2000-08-10)
S-Adenosyl-l-methionine-dependent protein arginine N-methyltransferases (PRMTs) catalyze the methylation of arginine residues within a variety of proteins. At least four distinct mammalian family members have now been described, including PRMT1, PRMT3, CARM1/PRMT4, and JBP1/PRMT5. To more fully define the physiological role
L L Belyanskaya et al.
The Journal of biological chemistry, 276(22), 18681-18687 (2001-03-30)
In contrast to the knowledge regarding the function of chimeric Ewing sarcoma (EWS) fusion proteins that arise from chromosomal translocation, the cellular function of the RNA binding EWS protein is poorly characterized. EWS protein had been found mainly in the
X Zhang et al.
The EMBO journal, 19(14), 3509-3519 (2000-07-19)
Protein arginine methylation has been implicated in signal transduction, nuclear transport and transcription regulation. Protein arginine methyltransferases (PRMTs) mediate the AdoMet-dependent methylation of many proteins, including many RNA binding proteins involved in various aspects of RNA processing and/or transport. Here

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