AB1892
Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, NT
Chemicon®, from rabbit
Sinonimo/i:
CX3CR1
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
rabbit
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Reattività contro le specie
rat, human, mouse
Produttore/marchio commerciale
Chemicon®
tecniche
immunohistochemistry: suitable
western blot: suitable
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... CX3CR1(1524)
Descrizione generale
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively (1-4). The seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by facktokine (6). CX3CR1 mediates leukocyte migration and adhesion.
Specificità
Specific for human C-X-X-X-C Chemokine Receptor 1 (CX3CR1) at the Extracellular loop. The sequence is identical to that of rat and differs from that of mouse by only one amino acid.
Immunogeno
Epitope: N-terminus
Synthetic peptide from the N-terminal of human CX3CR1.
Applicazioni
Detect C-X-X-X-C Chemokine Receptor 1 using this Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, N-terminus validated for use in IH & WB.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Western blot: 1:500 - 1:2000 (Human spleen tissue lysate can be used as positive control and an approximately 50 kDa band can be detected)
Immunohistochemistry in frozen sections
Optimal working dilutions must be determined by end user.
Immunohistochemistry in frozen sections
Optimal working dilutions must be determined by end user.
Stato fisico
Format: Purified
Purified immunoglobulin. 100 μg purified IgG in 100 μL of PBS containing 0.2% sodium azide.
Stoccaggio e stabilità
Store at 2-8°C for up to 12 months.
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Motore di ricerca dei prodotti.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Spatial and temporally restricted expression of chemokines and chemokine receptors in the developing human kidney.
Hermann-Josef Grone, Clemens D Cohen, Elisabeth Grone, Claudia Schmidt, Matthias Kretzler et al.
Journal of the American Society of Nephrology null
Xilei Li et al.
Frontiers in neuroscience, 15, 620525-620525 (2021-04-13)
Previous studies have proved that peripheral nerve injury is involved in the pathogenesis of neuropathic pain (NP). The peripheral nerve injury primes spinal M1 microglia phenotype and produces pro-inflammatory cytokines, which are responsible for neurotoxic and neuronal hyper-excitable outcomes. Spinal
C J Raport et al.
Gene, 163(2), 295-299 (1995-10-03)
A polymerase chain reaction (PCR) strategy with degenerate primers was used to identify novel G-protein-coupled receptor-encoding genes from human genomic DNA. One of the isolated clones, termed V28, showed high sequence similarity to the genes encoding human chemokine receptors for
C Combadiere et al.
DNA and cell biology, 14(8), 673-680 (1995-08-01)
A human cDNA encoding a putative G protein-coupled receptor designated chemokine beta receptor-like 1 (CMKBRL1) was isolated from an eosinophilic leukemia library. Its deduced sequence is approximately 40% identical to previously cloned receptors for the beta chemokines macrophage inflammatory protein-1
T Imai et al.
Cell, 91(4), 521-530 (1997-12-09)
Leukocyte trafficking at the endothelium requires both cellular adhesion molecules and chemotactic factors. Fractalkine, a novel transmembrane molecule with a CX3C-motif chemokine domain atop a mucin stalk, induces both adhesion and migration of leukocytes. Here we identify a seven-transmembrane high-affinity
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.