8.51011

MSNT

Novabiochem^®

• Sinonimo/i: MSNT, 1-(Mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole
• Formula empirica (notazione di Hill): C₁₁H₁₂N₄O₄S
• Numero CAS: 74257-00-4
• Peso molecolare: 296.30
• Numero MDL: MFCD00009754
• Codice UNSPSC: 12352005

Proprietà

• Nome Commerciale: Novabiochem^®
• Saggio: ≥95.0% (HPLC)
• Forma fisica: powder
• Impiego in reazioni chimiche: reaction type: Coupling Reactions
• Produttore/marchio commerciale: Novabiochem^®
• Temperatura di conservazione: 15-25°C
• InChI: 1S/C11H12N4O4S/c1-7-4-8(2)10(9(3)5-7)20(18,19)14-6-12-11(13-14)15(16)17/h4-6H,1-3H3; SFYDWLYPIXHPML-UHFFFAOYSA-N

Descrizione

Descrizione generale

This versatile reagent was originally used as a coupling reagent in phosphotriester oligonucleotide synthesis [1-3]. In recent years, it has been increasingly used for the esterification of Fmoc-amino acids onto solid phase synthesis supports [4-12]. It has proved particularly effective in difficult cases involving unreactive linkers [8, 9] or enantiomerization prone amino acids [7]. In an investigation [6] into ester formation, in which the alcohol or carboxylic acid component was immobilized on a solid support, MSNT was found to give the best results of all the reagents tested (DCC, DCC/HOBt, DCC/DMAP, Ph₃P/DEAD).

The product number for this product was previously 01-62-0021.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Linkage

Replaces: 01-62-0021

Risultati analitici

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 95.0 % (a/a)

Note legali

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany