8.02301

1,1′-Carbonyldiimidazole

for synthesis

• Sinonimo/i: 1,1′-Carbonyldiimidazole
• Formula empirica (notazione di Hill): C₇H₆N₄O
• Numero CAS: 530-62-1
• Peso molecolare: 162.15
• Numero MDL: MFCD00005286
• Codice UNSPSC: 12352115
• Numero indice EU: 208-488-9
• NACRES: NA.22

Proprietà

• Livello qualitativo: 200
• Saggio: ≥97.0% (GC)
• Forma fisica: powder
• Potenza: 1071 mg/kg LD₅₀, oral (Rat)
• Impiego in reazioni chimiche: reaction type: Carbonylations
• pH: 7.7 (20 °C, 50 g/L in H₂O)
• Punto di fusione: 116-120 °C
• applicazioni: peptide synthesis
• Temperatura di conservazione: 2-8°C
• InChI: 1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H; PFKFTWBEEFSNDU-UHFFFAOYSA-N

Descrizione

Applicazioni

• Facile Synthesis of 2-(1H-indol-3-yl)-acetamides: Synthesizing acetamides using 1,1′-Carbonyldiimidazole, showcasing its role in forming a reactive intermediate with pyridine (KMK Kanwal, B Fatima, B Bano, U Salar - J. Chem. Soc. Pak, 2016).


• Nanoflower Enhanced Capacitive Aptasensor: The synthesis of a novel hybrid nanoflower using 1,1′-Carbonyldiimidazole for attomolar detection limits in milk contamination detection (IG Subramani, V Perumal, SCB Gopinath - Scientific Reports, 2021).


• Thermodynamic Properties Analysis: The data on the thermodynamic properties of 1,1′-Carbonyldiimidazole and its applications in understanding material behaviors (JB Campos, JM Toro Jauregui - Journal of the Mexican Chemical Society, 2020).


• Synthesis of Deuterated Triacylglycerides: The use of 1,1′-Carbonyldiimidazole in the synthesis of medium chain triglyceride oil, highlighting its application in food emulsion studies (K Schwärzer, T Heiden‐Hecht, Y Chen - European Journal of Organic Chemistry, 2023).


• Mechanochemical Carbamate Synthesis: The use of 1,1′-Carbonyldiimidazole in an eco-friendly synthesis of carbamates, demonstrating its versatility as an acyl transfer reagent (M Lanzillotto, L Konnert, F Lamaty - ACS Sustainable Chemistry & Engineering, 2015).

Risultati analitici

Assay (GC, area%): ≥ 97.0 % (a/a)
Melting range (lower value): ≥ 115 °C
Melting range (upper value): ≤ 121 °C
Identity (IR): passes test

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302 - H314
• Consigli di prudenza: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Codice della classe di stoccaggio: 8A - Combustible, corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable