655207

TWEEN^® 80

protein grade detergent, 10% solution, sterile-filtered, for immunoprecipitation and for the solubilization of membrane-bound proteins

• Sinonimo/i: Monooleato di polietilenglicole sorbitano, Monooleato di poliossietilene sorbitano, POE (20) sorbitano monooleato, Polisorbato 80
• Numero CAS: 9005-65-6
• Numero MDL: MFCD00082107
• Codice UNSPSC: 12161902
• NACRES: NA.25

Proprietà

• Livello qualitativo: 100
• Forma fisica: liquid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Numero d'aggregazione: 58
• Impurezze: ≤200 μM Aldehyde; ≤200 μM peroxide
• Colore: clear colorless
• CMC: 12 μM (HLB number 15)
• Condizioni di spedizione: ambient
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
• InChI: 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+; RGPBUVUVZKQNHD-MDZDMXLPSA-N

Descrizione

Descrizione generale

Conductivity:≤50 µmhos.

Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins (aggregation number: 58; conductivity: <50 µmhos; CMC: 12 µM; HLB number: 15). Supplied as a 10% (W/W) solution of PROTEIN GRADE TWEEN 80 detergent.

Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins. Supplied as a 10% (W/W) solution of PROTEIN GRADE TWEEN 80 detergent.

Applicazioni

• Performance of β-carotene-loaded nanostructured lipid carriers under dynamic in vitro digestion system: Influence of the emulsifier type.: This paper discusses the performance of β-carotene-loaded nanostructured lipid carriers, where TWEEN 80 is utilized as an emulsifier. The study highlights its impact on the stability and bioaccessibility of β-carotene during digestion, offering valuable insights for food science and nutraceuticals applications (Lüdtke FL et al., 2024).


• Fabrication and characterization of transdermal delivery of ribociclib nanoemulgel in breast cancer treatment.: This study explores the use of TWEEN 80 in developing a transdermal nanoemulgel for the delivery of ribociclib, enhancing its therapeutic efficacy against breast cancer. The work focuses on innovative drug delivery systems that improve patient compliance and drug stability (Makeen HA et al., 2024).


• A novel antifungal nanoemulsion based on reuterin-assisted synergistic essential oils: Preparation and in vitro/in vivo characterization.: Here, TWEEN 80 is used to create a potent antifungal nanoemulsion, incorporating reuterin and essential oils. The study emphasizes the potential of nanoemulsions to significantly enhance the antifungal activity of natural compounds, promising applications in food preservation and safety (Nikkhah M et al., 2024).


• Development and characterization of edible and active coating based on xanthan gum nanoemulsion incorporating betel leaf extract for fresh produce preservation.: This investigation uses TWEEN 80 in a xanthan gum-based nanoemulsion, integrating betel leaf extract for the preservation of fresh produce. It highlights the role of such nanoemulsions in extending the shelf life of perishable foods, with significant implications for the food industry (Aayush K et al., 2024).

Confezionamento

Packaged under inert gas

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

Supplied as a 10% (W/W) aqueous solution.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

PROTEIN GRADE is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): >235.4 °F - closed cup
• Punto d’infiammabilità (°C): > 113 °C - closed cup