16-155
Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, FITC conjugate
Upstate®, from mouse
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About This Item
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Coniugato
FITC conjugate
Forma dell’anticorpo
purified antibody
Tipo di anticorpo
primary antibodies
Clone
monoclonal
Reattività contro le specie (prevista in base all’omologia)
all
Produttore/marchio commerciale
Upstate®
tecniche
immunocytochemistry: suitable
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
phosphorylation (pSer/pThr)
Descrizione generale
This antibody recognizes a variety of proteins that are phosphorylated during mitosis.
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
Applicazioni
Detect phospho-Ser/Thr-Pro also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, FITC conjugate (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC.
For applications in which an FITC conjugate is advantageous, such as ICC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Cell Cycle, DNA Replication & Repair
Qualità
routinely evaluated in immunocytochemistry on A431 mitotic cells fixed with 3.7% paraformaldehyde
Stato fisico
TBS, pH 8.0, 0.05% sodium azide and 30% glycerol
Stoccaggio e stabilità
Stable for 1 year at -20°C from date of shipment. Store in the dark. For maximum recovery of product, centrifuge the vial.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Certificati d'analisi (COA)
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
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Organic & Biomolecular Chemistry null
Cancer cell, 26(3), 414-427 (2014-09-02)
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Molecular Biology of the Cell, 5, 135-145 (1994)
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research null
The mitosis-specific monoclonal antibody MPM-2 recognizes phosphoproteins associated with the nuclear envelope in Chlamydomonas reinhardtii cells.
European Journal of Cell Biology, 51, 272-278 (1990)
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