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Merck
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Key Documents

16-155

Sigma-Aldrich

Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, FITC conjugate

Upstate®, from mouse

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Coniugato

FITC conjugate

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

monoclonal

Reattività contro le specie (prevista in base all’omologia)

all

Produttore/marchio commerciale

Upstate®

tecniche

immunocytochemistry: suitable

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

phosphorylation (pSer/pThr)

Descrizione generale

This antibody recognizes a variety of proteins that are phosphorylated during mitosis.

Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)

Applicazioni

Detect phospho-Ser/Thr-Pro also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, FITC conjugate (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC.
For applications in which an FITC conjugate is advantageous, such as ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualità

routinely evaluated in immunocytochemistry on A431 mitotic cells fixed with 3.7% paraformaldehyde

Stato fisico

TBS, pH 8.0, 0.05% sodium azide and 30% glycerol

Stoccaggio e stabilità

Stable for 1 year at -20°C from date of shipment. Store in the dark. For maximum recovery of product, centrifuge the vial.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Timothy R Rudd,Katarzyna A Uniewicz,Alessandro Ori,Scott E Guimond,Mark A Skidmore et al.
Organic & Biomolecular Chemistry null
William Clay Gustafson et al.
Cancer cell, 26(3), 414-427 (2014-09-02)
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Kuang, J, et al.
Molecular Biology of the Cell, 5, 135-145 (1994)
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Shan, W; Akinfenwa, PY; Savannah, KB; Kolomeyevskaya, N; Laucirica, R; Thomas, DG; Odunsi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null
The mitosis-specific monoclonal antibody MPM-2 recognizes phosphoproteins associated with the nuclear envelope in Chlamydomonas reinhardtii cells.
Harper, J D, et al.
European Journal of Cell Biology, 51, 272-278 (1990)

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

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