14-246-M
p38γ/SAPK3 Protein, active, 10 µg
Active, recombinant GST fusion protein corresponding to full length human p38γ/SAPK3, for use in Kinase Assays.
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About This Item
Codice UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Origine biologica
human
Livello qualitativo
Ricombinante
expressed in E. coli
PM
Mw 69 kDa
Produttore/marchio commerciale
Upstate®
tecniche
activity assay: suitable (kinase)
N° accesso NCBI
N° accesso UniProt
Informazioni sul gene
human ... PEBP1(5037)
Descrizione generale
Product Source: expressed in E. coli
Recombinant GST fusion protein corresponding to full length human p38γ/SAPK3
Azioni biochim/fisiol
Protein Target: p38γ/SAPK3
Target Sub-Family: CMGC
Qualità
Routinely evaluated by phosphorylation of MBP in vitro
Stoccaggio e stabilità
6 months at -70°C
Altre note
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Skin Sens. 1
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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The hepatitis B virus HBx protein inhibits caspase 3 activity
Gottlob, K., et al
The Journal of Biological Chemistry, 273, 33347-33353 (1998)
A Cuenda et al.
The EMBO journal, 16(2), 295-305 (1997-01-15)
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution, was transfected into several mammalian cell lines and shown to be activated in response to cellular stresses, interleukin-1 (IL-1) and tumour necrosis factor (TNF)
S P Davies et al.
The Biochemical journal, 351(Pt 1), 95-105 (2000-09-22)
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine/threonine-specific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many
Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif
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