13-107
Core Histones
Highly pure core histones proteins (H2A, H2B, H3 and H4) including H1 purified from chicken erythrocytes, suitable as a substrate for histone modification assays (HAT, HDAC, DNMT) and nucleosome assembly studies.
Sinonimo/i:
Core Histone Proteins
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About This Item
Codice UNSPSC:
12352200
eCl@ss:
32160405
NACRES:
NA.32
Prodotti consigliati
Origine biologica
chicken
Produttore/marchio commerciale
Upstate®
tecniche
activity assay: suitable (histone acetyltransferase (HAT))
Condizioni di spedizione
dry ice
Descrizione generale
Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Some histones function as spools for the thread-like DNA to wrap around forming a nucleosome. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional H1 histone proteins are associated with each nucleosome to maintain the chromosome structure.
Applicazioni
Core histones and histone H1, purified from chicken erythrocytes; suitable as a substrate for HAT assays; purity = 90%
Qualità
rountinely evaluated by immunoblot using Anti-Histone H3 (05-499) and Anti-Histone H4 (07-108)
Stato fisico
Lyophilized
Stoccaggio e stabilità
Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -70°C
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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