126654
Albumin, Human Serum, Non-denatured
Sinonimo/i:
Albumin, Human Serum, Non-denatured
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About This Item
Prodotti consigliati
Descrizione
Merck USA index - 14, 8468
Saggio
≥95% (SDS-PAGE)
Stato
lyophilized solid (Salt-free)
Produttore/marchio commerciale
Calbiochem®
Condizioni di stoccaggio
OK to freeze
tecniche
protein quantification: suitable
pI
4.7
Solubilità
water: 20 mg/mL
Condizioni di spedizione
ambient
Temperatura di conservazione
2-8°C
Stringa SMILE
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Descrizione generale
High purity plasma protein prepared under non-denaturing conditions.
Human serum albumin (HSA) is the most abundant protein present in the plasma. It is a monomeric multi-domain macromolecule comprising three homologous domains, numbered I, II, and III. Each domain consists of subdomains A and B with common structural motifs. The HSA gene is mapped to the human chromosome 4q13.3.
Applicazioni
Albumin, human serum, non-denatured has been used:
- to determine the contribution of albumin protein complexes to esterase activity in saliva,
- in tris buffer for monomer degradation studies and in protein adhesion assay
- to study the effect of Cu2+ and Zn2+ ions on human serum albumin interaction with plasma unsaturated fatty acids
Azioni biochim/fisiol
Human serum albumin (HSA) functions as a carrier for fatty acids, steroids, and thyroid hormones. It is used as a supplement in cell culture medium to produce vaccines and pharmaceuticals. HSA is a potential biomarker for various diseases, like cancer, rheumatoid arthritis, ischemia, and post-menopausal obesity. It is also used to treat surgical blood loss, trauma, hemorrhage, and cardiopulmonary bypass. HSA is implicated in biological applications such as implantable biomaterials, surgical adhesives and sealants, and bio chromatography.
Attenzione
Toxicity: Standard Handling (A)
Nota sulla preparazione
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Ricostituzione
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Altre note
Travis, J., and Pannell, R. 1973. Clin. Chem. Acta49, 49.
Note legali
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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