12-523

GST, 6 His-tagged

• Sinonimo/i: GST Fusion Protein
• Codice UNSPSC: 12352204
• eCl@ss: 32160405
• NACRES: NA.41

Proprietà

• Forma fisica: liquid
• Livello qualitativo: 100
• Produttore/marchio commerciale: Upstate^®
• tecniche: affinity chromatography: suitable
• N° accesso NCBI: NM_000852.2
• N° accesso UniProt: P09211
• Condizioni di spedizione: dry ice

Descrizione

Descrizione generale

Glutathione S-transferase (GST) belongs to three families of proteins distinguished as cytosolic, mitochondrial, and microsomal GST. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α, κ, μ, ω, π, σ, θ, and ζ. This product is a C-terminal 6 histidine-tagged, recombinant full-length glutathione S-transferase (GST).

Azioni biochim/fisiol

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in phase II detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Stato fisico

50mM Tris-HCl, pH 8, 150mM NaCl, 20% glycerol

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2