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Merck
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Documenti fondamentali

07-1406

Sigma-Aldrich

Anti-GLUT-5 Antibody, a.a. 490-502

serum, from rabbit

Sinonimo/i:

Fructose transporter, Glucose transporter type 5, small intestine, glucose transporter-like protein 5, solute carrier family 2 (facilitated glucose transporter),

member 5, solute carrier family 2 (facilitated glucose/fructose

transporte

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

rat, guinea pig, mouse

tecniche

western blot: suitable

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

mouse ... Slc2A5(56485)

Descrizione generale

A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels.

Specificità

Recognizes GLUT-5.

Immunogeno

Epitope: C-terminus
Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse.

Applicazioni

Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualità

Evaluated by Western Blot in Mouse kidney lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.

Descrizione del bersaglio

Approx. 54 kDa

Linkage

Replaces: AB1348

Stato fisico

Liquid containing 0.05% sodium azide.
Unpurified rabbit serum

Stoccaggio e stabilità

Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles.

Risultati analitici

Control
Mouse kidney lysate.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


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Irene Zwarts et al.
Scientific reports, 9(1), 9299-9299 (2019-06-28)
Fructose has become a major constituent of our modern diet and is implicated as an underlying cause in the development of metabolic diseases. The fructose transporter GLUT5 (SLC2A5) is required for intestinal fructose absorption. GLUT5 expression is induced in the
Ana Andres-Hernando et al.
Cell metabolism, 32(1), 117-127 (2020-06-06)
Intake of fructose-containing sugars is strongly associated with metabolic syndrome. Compared with other sugars, dietary fructose is uniquely metabolized by fructokinase. However, the tissue-specific role of fructokinase in sugar-induced metabolic syndrome, and the specific roles of glucose and fructose in

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