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Merck
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Key Documents

07-140

Sigma-Aldrich

Anti-STAT2 Antibody

Upstate®, from rabbit

Sinonimo/i:

Anti-IMD44, Anti-ISGF-3, Anti-P113, Anti-PTORCH3, Anti-STAT113

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

mouse

Produttore/marchio commerciale

Upstate®

tecniche

electrophoretic mobility shift assay: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_005419

N° accesso UniProt

P52630

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... STAT2(6773)

Specificità

STAT2

Immunogeno

GST-fusion protein corresponding to residues 672-925 of murine STAT2

Applicazioni

Anti-STAT2 Antibody is a Rabbit Polyclonal Antibody for detection of STAT2 also known as Signal Transducer & Activator of Transcription 2 & has been tested in EMSA, IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Qualità

routinely evaluated by immunoblot on

Descrizione del bersaglio

130kDa

Stato fisico

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Affinity Chromatography

Stoccaggio e stabilità

2 years at -20°C

Risultati analitici

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.
Zhu Guo, Sanjay Garg, Karen M Hill, Lakshmi Jayashankar, Myesha R Mooney, Mary Hoelscher et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)
Connie C Qiu et al.
Oncoimmunology, 10(1), 1860477-1860477 (2021-01-19)
STAT2 is a central component of the ISGF3 transcriptional complex downstream of type I interferon (IFN-I) signaling. The significance of in vivo IFN-I/STAT1 signals in cDCs is well-established in the generation of antitumor cytotoxic T cell (CTL) responses. However, the role
Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
Zurney, J; Kobayashi, T; Holm, GH; Dermody, TS; Sherry, B
Journal of virology null
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.
Lagor, WR; Fields, DW; Bauer, RC; Crawford, A; Abt, MC; Artis, D; Wherry, EJ; Rader, DJ
Atherosclerosis null
M Matsumoto et al.
Biological chemistry, 380(6), 699-703 (1999-08-03)
The interferon-stimulated gene factor 3 (ISGF3) transcription factor has been extensively studied in the context of the type I interferon (IFN-alpha/beta)-mediated antiviral response; it consists of the major DNA-binding component p48, and the signal transducers and activators of transcription (Stat)1
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