07-104

Anti-IGF2 mRNA-binding protein 3 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, insulin-like growth factor 2 mRN
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human, mouse, canine
• Reattività contro le specie (prevista in base all’omologia): rhesus monkey (based on 100% sequence homology), dog (based on 100% sequence homology), horse (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• tecniche: western blot: suitable
• N° accesso NCBI: NP_006538
• N° accesso UniProt: O00425
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... IGF2BP3(10643)

Descrizione

Descrizione generale

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor 2 leader 3 mRNA and may repress translation of insulin-like growth factor 2 during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq].

Specificità

This antibody recognizes IGF2 mRNA-binding protein 3 at the C-terminus.

Immunogeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to human IGF2 mRNA-binding protein 3 at and around the C-terminus.

Applicazioni

Research Category
Apoptosis & Cancer

Research Sub Category
Growth Factors & Receptors

This Anti-IGF2 mRNA-binding protein 3 Antibody is validated for use in WB for the detection of IGF2 mRNA-binding protein 3.

Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP.

Qualità

Evaluated by Western Blot in Hek293 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate.

Descrizione del bersaglio

64 kDa was observed. Predicted to cross-react with all the Isoforms of IGF2BP3.

Stato fisico

Affinity purified

Purified rabbit serum in PBS with 0.09% azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Hek293 cell lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable