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Merck
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Key Documents

05-753

Sigma-Aldrich

Anti-WT1 Antibody, clone 6F-H2

clone 6F-H2, Upstate®, from mouse

Sinonimo/i:

Anti-AWT1, Anti-GUD, Anti-NPHS4, Anti-WAGR, Anti-WIT-2, Anti-WT-1, Anti-WT33

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

6F-H2, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Upstate®

tecniche

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG1

N° accesso NCBI

NM_024426

N° accesso UniProt

P19544

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... WT1(7490)

Specificità

WT1

Immunogeno

6His-tagged fusion protein corresponding to residues 1-181 of human WT1 (Wilms tumor)

Applicazioni

Anti-WT1 Antibody, clone 6F-H2 is a Mouse Monoclonal Antibody for detection of WT1 also known as Wilms′ Tumor & has been tested in WB, ICC & IHC.

Qualità

routinely evaluated by immunoblot on RIPA lysates from Jurkat and Raji cells

Descrizione del bersaglio

55-60kDa

Stato fisico

Format: Purified

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

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Toru Sakairi et al.
American journal of physiology. Renal physiology, 298(3), F557-F567 (2009-12-04)
Evidence suggests that loss of podocytes into urine contributes to development of glomerular diseases; shed podocytes are frequently viable and proliferate in culture conditions. To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term
Zenglai Tan et al.
Scientific reports, 8(1), 16618-16618 (2018-11-11)
The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from
Toru Sakairi et al.
American journal of physiology. Renal physiology, 299(4), F802-F809 (2010-07-30)
We transformed mouse podocytes by ectopic expression of cyclin-dependent kinase 4 (CDK4). Compared with podocytes transformed with a thermo-sensitive SV40 large T antigen mutant tsA58U19 (tsT podocytes), podocytes transformed with CDK4 (CDK4 podocytes) exhibited significantly higher expression of nephrin mRNA.
Rosalba Parenti et al.
PloS one, 9(12), e114333-e114333 (2014-12-05)
Wilms' tumor gene 1 (WT1) plays complex roles in tumorigenesis, acting as tumor suppressor gene or an oncogene depending on the cellular context. WT1 expression has been variably reported in both benign and malignant peripheral nerve sheath tumors (MPNSTs) by
Aleksandra Rak-Raszewska et al.
Developmental dynamics : an official publication of the American Association of Anatomists (2021-09-09)
Tissue organoids derived from primary cells have high potential for studying organ development and diseases in numerous organs. They recreate the morphological structure and mimic the functions of given organ while being compact in size, easy to produce, and suitable
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