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Key Documents

04-298

Sigma-Aldrich

Anti-IGF1 Receptor (CT) Antibody, clone 7G11

clone 7G11, Upstate®, from mouse

Sinonimo/i:

insulin-like growth factor 1

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

7G11, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Upstate®

tecniche

ELISA: suitable
western blot: suitable

Isotipo

IgG1

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... IGF1(3479)

Specificità

Recognizes C-terminus of IGF1 receptor

Immunogeno

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of the C-terminus in human IGF1

Applicazioni

Anti-IGF1 Receptor (C-terminus) Antibody, clone 7G11 detects level of IGF1 Receptor (C-terminus) & has been published & validated for use in ELISA & WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualità

Routinely evaluated by immunoblot.

Descrizione del bersaglio

90 kDa

Stato fisico

100 &mciro;g of purified mouse monoclonal IgG lyophilized in 2X PBS containing 0.09% sodium azide, PEG, and sucrose
Format: Purified
Subsequent thiophilic adsorption and size exclusion chromatography

Stoccaggio e stabilità

2 years at -20°C from date of shipment. Reconstitute prior to use. Reconstitute with 1 mL H2O for 15 min at room temperature. Reconstituted aliquots should be stored frozen at -80°C. Thawed aliquots may be stored at 4°C for up to 3 months. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Risultati analitici

Control
Includes untreated A431 lysate as a positive control.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids


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M Wallander et al.
Diabetologia, 49(10), 2247-2255 (2006-09-07)
Low levels of IGF-I are associated with increased risk of cardiovascular disease and type 2 diabetes. The aim of this study was to investigate the IGF-I system in patients with acute myocardial infarction (AMI) without previously known diabetes. One hundred
Thomas Thum et al.
Circulation research, 100(3), 434-443 (2007-01-20)
Aging is associated with an increased risk for atherosclerosis. A possible cause is low numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair damaged vascular walls. We hypothesized that decreased levels of insulin-like growth factor-1 (IGF-1) during age
Shuhua Chen et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(4), 1813-1824 (2020-07-08)
Previous studies demonstrated that the endogenous neurosteroid allopregnanolone (Allo) promotes regeneration of rodent and human neural progenitor/neural stem cells (NSCs) in vitro and in vivo, and restores neurogenesis and cognitive function in the male triple transgenic mouse model of Alzheimer's

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