04-1470

Anti-OX40L (CD252) Antibody, clone RM134L

clone RM134L, from rat

• Sinonimo/i: Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rat
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: RM134L, monoclonal
• Reattività contro le specie: mouse
• tecniche: flow cytometry: suitable; immunohistochemistry: suitable
• Isotipo: IgG2bκ
• N° accesso NCBI: NP_033478
• N° accesso UniProt: P43488
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Tnfsf4(22164)

Descrizione

Descrizione generale

OX40L (Tumor necrosis factor ligand superfamily member 4; or CD252) is the endogenous ligand of the OX40 receptor. OX40 is localized on activated T-cells and propagates the immune response by promoting division and survival of T-cells, thereby increasing the population of memory CD4 and CD8 T cells produced in response to antigen detection. The OX40/OX40L may also regulate cytokine production and suppress the activity of T-regulatory cells. OX40/OX40L is therefore an important mediator of the immune response. Previous studies have suggested that OX40 signaling maybe involved in the development of autoimmune diseases.

Specificità

This antibody recognizes the extracellular domain of OX40L.

Immunogeno

Mouse OX40L cDNA-transfected NRK cells

Applicazioni

Anti-OX40L (CD252) Antibody, clone RM134L detects level of OX40L (CD252) & has been published & validated for use in Flow Cytometry & IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse lung tissue. (Hoshino, A., et al. (2003). Eur. J. Immunol. 33:861–869.)

Qualità

Evaluated by Flow Cytometry in mouse OX40L/L5178Y cells.

Flow Cytometry Analysis: 10 µg of this antibody detected OX40L in mouse OX40L/L5178Y cells.

Descrizione del bersaglio

22 kDa calculated

Stato fisico

Format: Purified

Risultati analitici

Control
Mouse OX40L/L5178Y cells

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable