03-0203-00
SMC® Human GFAP High Sensitivity Immunoassay Kit
Sinonimo/i:
GFAP Single Molecule Counting Kit, GFAP ultra-sensitive immunoassay, Glial fibrillary acidic protein immunoassay kit
About This Item
Prodotti consigliati
Reattività contro le specie
human
Livello qualitativo
Produttore/marchio commerciale
SMC®
assay range
sensitivity: 0.23 pg/mL
(Lower Limit of Quantification)
inter-assay cv: ≤6%
intra-assay cv: ≤5%
(Intra-assay CV n=5; Inter-assay n=3)
Categorie correlate
Descrizione generale
Glial fibrillary acidic protein (GFAP) is a type III intermediate filament protein produced notably by astrocytes during CNS development, and functions in astrocyte regeneration, plasticity, and also contributes to function of the blood brain barrier. GFAP is a potential biomarker in a number of neurodegenerative diseases as well as in traumatic brain injury. There is much interest today in measuring GFAP levels in low abundance, because not only does it make it possible to evaluate this protein as a blood biomarker, but also enables researchers to study the downregulation of GFAP in therapeutic research. The new SMC® Human GFAP High Sensitivity Immunoassay Kit enables accurate measurement of this protein in human serum, plasma, and cerebrospinal fluid, harnessing the power of the SMCxPRO® ultrasensitive immunoassay system.
Specificità
Non Human Primate – 100%
Mouse – 100%
Rat – 100%
Canine – 100%
Feline – 100%
Note: This assay was tested for cross-reactivity with Ventimin, NFL, UCHL1 and total Tau. No cross-reactivity was detected with any of these analytes.
Applicazioni
This new streamline kit has the following features:
- Improved options for sample prep and incubation
- Lyophilization protein standard for uniform shipping and storage condition
- Increased reagent volumes to accommodate automation
- Able to achieve assay specifications on both SMCxPRO® and Erenna.
Research Category:
Neuroscience
neurological
Research Sub-Category:
Alzheimer′s Disease
Aging, Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
Componenti
- Assay Buffer
- GFAP Coated Beads
- Standard Diluent
- GFAP Detection Antibody
- GFAP Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
Specifiche
Minimum of 4 plasma samples spiked with average recovery of 115% with a range of 110-119%
Minimum of 5 CSF samples spiked with average recovery of 101% with a range of 95-106%
Note legali
Esclusione di responsabilità
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
Codice della classe di stoccaggio
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe di pericolosità dell'acqua (WGK)
WGK 3
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Contenuto correlato
Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.