P-096

Pregabalin-D₆ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₈D₆H₁₁NO₂
• Peso molecolare: 165.26
• Numero CE: 200-659-6
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Livello qualitativo: 300
• Forma fisica: liquid
• Caratteristiche: (Snap-N-Spike^®)
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 1.0 mg/mL in methanol
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: clinical testing
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C(C1=C2C(NC(CCOCCC(O)=O)=O)=CC=C1)N([C@H]3CCC(NC3=O)=O)C2=O.O=C(C4=C5C(NC(CCOCCC(O)=O)=O)=CC=C4)N([C@H]6CCC(NC6=O)=O)C5=O
• InChI: 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/i1D3,2D3; AYXYPKUFHZROOJ-WFGJKAKNSA-N

Descrizione

Descrizione generale

Sold under the trade name Lyrica^®, Pregabalin is an antiepileptic drug used for treatment of seizures, fibromyalgia, diabetic peripheral neuropathy, generalized anxiety disorder, and chronic neuropathic pain. This internal standard is suitable for pregabalin GC/MS or LC/MS testing or isotope dilution methods in forensic analysis, clinical toxicology, pain prescription monitoring, or urine drug testing.

Applicazioni

• Pregabalin-D₆ in Therapeutic Drug Monitoring: Pregabalin-D₆ serves as a crucial analytical standard in therapeutic drug monitoring using mass spectrometry, enhancing the precision of quantifying new-generation antiseizure medications among epilepsy patients (Kim et al., 2024).


• Multi-Component LC-MS/MS Analysis: Utilizing Pregabalin-D₆ as an internal standard, a multicomponent LC-MS/MS method was developed for drugs of abuse testing, showcasing its utility in comprehensive bioanalytical assays (Guterstam et al., 2024).


• Comprehensive Drug Class Screening: The use of Pregabalin-D₆ in the determination of various drug classes in whole blood exemplifies its role in complex toxicological screenings using LC-MS/MS, facilitating accurate metabolic studies (Jørgenrud et al., 2021).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Lyrica is a registered trademark of C.P. Pharmaceuticals International C.V.

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370
• Consigli di prudenza: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 49.5 °F
• Punto d’infiammabilità (°C): 9.7 °C