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N-003

Supelco

Norcocaine hydrochloride solution

1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C16H19NO4 · HCl
Numero CAS:
61585-22-6
Peso molecolare:
325.79
Numero MDL:
MFCD00242703
Codice UNSPSC:
41116107
ID PubChem:
329818391
NACRES:
NA.24

Grado

certified reference material

Livello qualitativo

300

Stato

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

1.0 mg/mL in acetonitrile (as free base)

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

forensics and toxicology

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1OC(=O)c3ccccc3)N2

InChI

1S/C16H19NO4.ClH/c1-20-16(19)14-12-8-7-11(17-12)9-13(14)21-15(18)10-5-3-2-4-6-10;/h2-6,11-14,17H,7-9H2,1H3;1H/t11-,12+,13-,14+;/m0./s1
RIPPXFWUYXTRNJ-BHARVXRSSA-N

Descrizione generale

Norcocaine is a primary urinary metabolite of the popular recreation drug cocaine. Cocaine is a central nervous system stimulant with appetite suppressant and topical anesthetic properties. This certified solution standard is applicable for use in urine drug testing, clinical toxicology or forensic toxicology applications by GC/MS or LC/MS.

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pittogrammi

FlameExclamation mark
GHS02,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H225,H302 + H312 + H332,H319

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

35.6 °F - closed cup

Punto d’infiammabilità (°C)

2 °C - closed cup

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Lot/Batch Number

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Kathleen M Kantak
Expert opinion on pharmacotherapy, 4(2), 213-218 (2003-02-04)
The past decade has seen the development of several vaccines against illicit-drugs. These include vaccines for producing antibodies against cocaine, heroin, methamphetamine and nicotine. The present focus is on anti-cocaine vaccines, as more research has been conducted with these vaccines
C W Schindler et al.
European journal of pharmacology, 431(1), 53-59 (2001-11-22)
The effects of cocaine and the cocaine metabolites norcocaine, ecgonine methyl ester, benzoylecgonine and cocaethylene were evaluated in conscious squirrel monkeys for their effects on blood pressure and heart rate. Norcocaine, ecgonine methyl ester and benzoylecgonine are produced in vivo
Christine Moore et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 859(2), 208-212 (2007-10-24)
A quantitative analytical procedure for the determination of cocaine, benzoylecgonine and cocaethylene and norcocaine in hair has been developed and validated. The hair samples were washed, incubated, and any drugs present were quantified using mixed mode solid-phase extraction and liquid
Hsiu-Li Su et al.
Electrophoresis, 29(20), 4270-4276 (2008-10-17)
We have employed a high-sensitivity on-line preconcentration method, cation-selective exhaustive injection (CSEI) and sweeping MEKC, for the analysis of cocaine, benzoylecgonine, norcocaine, and cocaethylene. We monitored the effects of several of the CSEI-sweeping-MEKC parameters - including the pH, the concentrations
P Pellinen et al.
Archives of toxicology, 74(9), 511-520 (2000-12-29)
The first step in the oxidative metabolism of cocaine is N-demethylation to norcocaine, which is further N-hydroxylated to more toxic N-hydroxynorcocaine. In this study we examined the kinetics of norcocaine N-hydroxylation mediated by cytochrome P450 (CYP) in mouse and human
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