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Key Documents

E-001

Supelco

Ecgonine methyl ester solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Sinonimo/i:

Ecgonine methyl ester solution

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About This Item

Formula empirica (notazione di Hill):
C10H17NO3
Numero CAS:
Peso molecolare:
199.25
Numero CE:
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

Concentrazione

1.0 mg/mL in acetonitrile

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

forensics and toxicology

Formato

single component solution

Temperatura di conservazione

−20°C

InChI

1S/C10H17NO3/c1-11-6-3-4-7(11)9(8(12)5-6)10(13)14-2/h6-9,12H,3-5H2,1-2H3/t6?,7?,8-,9+/m0/s1
QIQNNBXHAYSQRY-ABIFROTESA-N

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Descrizione generale

A certified Snap-N-Spike® solution standard suitable for use in LC/MS or GC/MS testing applications including forensic analysis, urine drug testing, and clinical toxicology. Ecgonine methyl ester is a major urinary metabolite of cocaine, a popular illicit drug well known as "crack" or the free base form of cocaine that can be smoked.

Applicazioni


  • Ecgonine methyl ester standard:The site- and species-specific hydrolysis rates of cocaine, demonstrating the importance of Ecgonine methyl ester as a reference standard in understanding cocaine metabolism pathways, aiding in pharmaceutical and forensic applications (Szocs et al., 2017).

  • Mass spectrometry reagent:Sensitive fluorescence probe was developed using molecularly imprinted polymers and Mn-doped ZnS quantum dots for the determination of cocaine and metabolites in urine, highlighting the use of Ecgonine methyl ester as a crucial mass spectrometry reagent for drug testing (Chantada-Vazquez et al., 2016).

  • Cocaine metabolite analysis:Magnetic molecularly imprinted polymers were developed for solid phase extraction of cocaine and metabolites in urine before high-performance liquid chromatography - tandem mass spectrometry, illustrating the essential role of Ecgonine methyl ester in the selective detection and quantification of cocaine metabolites (J Sanchez-Gonzzlez, et al., 2016).

  • Biochemical research chemicals:Porous membrane-protected molecularly imprinted polymer micro-solid-phase extraction method for analyzing urinary cocaine and its metabolites, validating Ecgonine methyl ester′s utility in biochemical and pharmacological studies (Sanchez-Gonzalez et al., 2015).

  • Forensic toxicology supplies:Employed peptides to trap cocaine, using solid phase extraction followed by liquid chromatography-mass spectrometry in plasma samples, underlining the application of Ecgonine methyl ester in forensic toxicology for precise and accurate drug monitoring (Mascini et al., 2013).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

FlameExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

35.6 °F - closed cup

Punto d’infiammabilità (°C)

2 °C - closed cup


Certificati d'analisi (COA)

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Supelco

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Marta Concheiro et al.
Journal of analytical toxicology, 31(9), 573-580 (2007-12-21)
A method, using 0.5 mL of urine, was developed for the simultaneous determination of ecgonine methyl ester, benzoylecgonine, morphine, codeine, 6-acetylmorphine, amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), and d-lysergic acid diethylamide (LSD). The analysis was performed by
C Pistos et al.
Rapid communications in mass spectrometry : RCM, 23(23), 3772-3780 (2009-11-11)
At present, no official criteria exist for drug identification using single quadrupole mass spectrometers although the European Union (EU) criteria for compound identification have been adopted. These criteria are evaluated with respect to the confirmation of cocaine and its metabolites
Rosa Cordero et al.
Journal of analytical toxicology, 34(9), 543-548 (2010-11-16)
The concentrations and ratios of cocaine, benzoylecgonine (BE), and ecgoninemethylester (EME) in 360 head hair segments and 34 pubic hair samples collected at coroner's postmortem examinations were reviewed. The cases included diverse histories and causes/circumstances of death. The hair was
Xiaobo Wang et al.
Se pu = Chinese journal of chromatography, 28(7), 673-676 (2010-11-05)
A method was developed for the simultaneous determination of cocaine (COC) and its metabolite ecgonine methyl ester (EME) in human blood using gas chromatography-mass spectrometry (GC-MS) and gas chromatography-flame ionization detection (GC-FID). The blood sample was prepared by microwave extraction
Karl B Scheidweiler et al.
Therapeutic drug monitoring, 32(5), 628-637 (2010-09-04)
Oral fluid is an attractive alternative matrix for drug testing with a noninvasive and directly observed collection, but there are few controlled cocaine administration studies to guide interpretation. While residing on a closed research unit for up to 10 weeks

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