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Key Documents

Altri documenti

B-034

Supelco

Bupropion hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C13H19Cl2NO
Numero CAS:
31677-93-7
Peso molecolare:
276.20
Numero CE:
200-659-6
Numero MDL:
MFCD00055209
Codice UNSPSC:
41116107
ID PubChem:
329773108
NACRES:
NA.24

Grado

certified reference material

Livello qualitativo

300

Forma fisica

liquid

Caratteristiche

SNAP-N-SPIKE®, SNAP-N-SHOOT®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

1.0 mg/mL in methanol (as free base)

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

clinical testing

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1

InChI

1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H
HEYVINCGKDONRU-UHFFFAOYSA-N

Informazioni sul gene

human ... SLC6A2(6530) , SLC6A3(6531)

Categorie correlate

Descrizione generale

A certified solution standard suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research. Bupropion is an antidepressant and smoking cessation drug sold under the trade names Wellbutrin® and Zyban®.

Applicazioni


  • Investigation of neurotoxic effects: Research on propofol′s potential neurotoxic impact on the hippocampus has deepened understanding of its effects on mitochondrial function. (Ebrahimi et al., 2024).

  • Enhancement of cardiopulmonary bypass outcomes: Propofol is used in clinical trials to explore its efficacy in reducing biomarkers of organ injury during cardiac surgery. (Smartt et al., 2024).

  • Development of nanoencapsulation techniques: Propofol is being researched for its encapsulation in nanocarriers to improve its delivery efficiency and reduce side effects. Such innovations in drug delivery are aimed at enhancing the pharmacological profile of anesthetics, making them safer and more effective (Abdoullateef et al., 2024).


Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Wellbutrin is a registered trademark of GlaxoSmithKline LLC
Zyban is a registered trademark of Everris International B.V.

Avvertenze

Danger

Indicazioni di pericolo

H225 - H301 + H311 + H331 - H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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3′-Chloropropiophenone 98%

Sigma-Aldrich

248193

3′-Chloropropiophenone

(2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC)

Sigma-Aldrich

H3167

(2S,3S)-Hydroxybupropion hydrochloride

Oxazepam solution 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

O-902

Oxazepam solution

Bromina reagent grade

Sigma-Aldrich

207888

Bromina

Idrossido di ammonio ACS reagent, 28.0-30.0% NH3 basis

Sigma-Aldrich

221228

Idrossido di ammonio

Danielle Baribeau et al.
Journal of addiction medicine, 7(3), 216-217 (2013-03-23)
Bupropion is an antidepressant commonly prescribed as a smoking cessation aid. It has effects on dopamine and norepinephrine, and can lower seizure threshold, particularly in overdose. Several cases of recreational use of bupropion via nasal insufflation have been reported in
P L Bölcskei et al.
Deutsche medizinische Wochenschrift (1946), 138(17), 902-907 (2013-04-18)
Smoking causes about 5 Million deaths worldwide every year. Prevention and cessation of smoking should therefore be one of the most important public health priorities. The family doctor as a trusted contact and representative of the health care system plays
Rapid assessment of cardiovascular risk among users of smoking cessation drugs within the US Food and Drug Administration's Mini-Sentinel program.
Sengwee Toh et al.
JAMA internal medicine, 173(9), 817-819 (2013-03-27)
Georgia Tsiapa et al.
In vivo (Athens, Greece), 27(2), 171-176 (2013-02-21)
Smoking is related to a great variety of pathological conditions, many of which affect the respiratory system, such as lung cancer and chronic obstructive pulmonary disease (COPD). Smoking cessation should be an integral part of the therapeutic approach to patients
Marney A White et al.
The Journal of clinical psychiatry, 74(4), 400-406 (2013-05-10)
Binge-eating disorder (BED) is defined by recurrent binge eating (eating unusually large quantities of food during which a subjective loss of control is experienced), marked distress about the binge eating, and the absence of inappropriate weight compensatory behaviors. BED is
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