890717O
Avanti
14:1 EPC (Tf Salt)
Avanti Research™ - A Croda Brand 890717O
Sinonimo/i:
1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)
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About This Item
Formula empirica (notazione di Hill):
C39H73F3NO11PS
Numero CAS:
Peso molecolare:
852.03
Codice UNSPSC:
12352211
NACRES:
NA.25
Prodotti consigliati
Stato
liquid
Confezionamento
pkg of 1 × 10 mg (890717O-10mg)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand 890717O
Tipo di lipide
transfection
cationic lipids
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Descrizione generale
Ethylphosphocholine (EPC) are amphiphilic cationic lipids containing hydrophilic headgroup and lipophilic tail.
Azioni biochim/fisiol
1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (14:1 EPC) is less toxic and is biodegradable. It is known to possess efficient DNA transfection activity. 14:1 EPC is very closely identical to the natural triacylglyceride lipids.
Confezionamento
5 mL Clear Glass Sealed Ampule (890717O-10mg)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
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The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
Boris G Tenchov et al.
Biochimica et biophysica acta, 1778(10), 2405-2412 (2008-08-30)
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Biochimica et biophysica acta, 1768(2), 375-386 (2006-12-13)
Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The large magnitude of the synergy
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