860658P
Avanti
sphinganine-d7
Avanti Research™ - A Croda Brand 860658P, powder
Sinonimo/i:
D-erythro-sphinganine-d7
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About This Item
Formula empirica (notazione di Hill):
C18H32D7NO2
Numero CAS:
Peso molecolare:
308.55
Codice UNSPSC:
12352211
NACRES:
NA.25
Prodotti consigliati
Stato
powder
Confezionamento
pkg of 1 × 1 mg (860658P-1mg)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand 860658P
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Stringa SMILE
OC[C@@](N)([H])[C@@](O)([H])CCCCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
Descrizione generale
Sphinganine-d7 is a deuterated derivative of sphinganine. Sphinganine, also called as dihydrosphingosine is a derivative of sphingosine. Sphinganines are produced in endoplasmic reticulum, by decarboxylating condensation of palmitoyl-CoA and serine.
Applicazioni
Sphinganine-d7 has been used as an internal standard for quantification of sphingolipid concentrations in plasma and tissue samples by high-performance liquid chromatography tandem mass spectrometry.
Azioni biochim/fisiol
Sphinganine (SPA) acts as a selective inhibitor of protein kinase C in intact human neutrophils. It may function a potential biomarker for the diagnosis of sphingolipidoses. SPA accumulation enables fumonisin B1 to stimulate apoptosis. It also has an ability to block cholesterol transport in Niemann-Pick Type C (NPC) disease.
Confezionamento
5 mL Amber Glass Screw Cap Vial (860658P-1mg)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
11 - Combustible Solids
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