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850697P

Avanti

06:0 PE

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, powder

Sinonimo/i:

PE(6:0/6:0)

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About This Item

Formula empirica (notazione di Hill):
C17H34NO8P
Numero CAS:
Peso molecolare:
411.43
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

powder

Confezionamento

pkg of 1 × 25 mg (850697P-25mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 850697P

Tipo di lipide

cardiolipins
phospholipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O

Categorie correlate

Descrizione generale

06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.
Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.

Applicazioni

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
  • as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
  • as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
  • as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants

06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).

Azioni biochim/fisiol

06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.
Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.

Confezionamento

5 mL Clear Glass Sealed Ampule (850697P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids


Certificati d'analisi (COA)

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Crystallographic identification of lipid as an integral component of the epitope of HIV broadly neutralizing antibody 4E10
Irimia A, et al.
Immunity, 44(1), 21-31 (2016)
Liquid chromatographic analysis of milk phospholipids with on-line pre-concentration
Fagan P, et al.
Journal of Chromatography A, 1054(1-2), 241-249 (2004)
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL
Rosie Dawaliby et al.
The Journal of biological chemistry, 291(7), 3658-3667 (2015-12-15)
Adequate membrane fluidity is required for a variety of key cellular processes and in particular for proper function of membrane proteins. In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid desaturation and cholesterol, although some
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5, 16787-16787 (2015)

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