QCRBNSET

QuicTPD CRBN ligand Set

Proprietà

• Confezionamento: pkg of 50 mg
• Livello qualitativo: 100
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

5-Amino Thalidomide, Lenalidomide, Pomalidomide and C-5 Lenalidomide are recruiters of CRBN protein that can be leveraged for targeted protein degradation research. They are provided at 50 mg each.

Applicazioni

Useful for construction of CRBN based partial protacs of full protacs, by utilizing the amine terminus to add suitable linkers with peptide coupling reactions. These can also be used as controls/competitors to confirm target engagement of putative protacs.

Caratteristiche e vantaggi

Quantities provided are sufficient to do atleast 96 reactions at 2 micromole each with a D2B approach with a library of suitable bifunctional linkers ending in carboxylic acid terminus to generate a library of partial protacs or full protacs.

Altre note

CRBN Ligand Set part of QuicTPD kit

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H312,H360FD,H373
• Consigli di prudenza: P202 - P260 - P264 - P280 - P301 + P310 - P302 + P352 + P312
• Classi di pericolo: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Repr. 1A - STOT RE 2
• Organi bersaglio: Blood
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3