QBD10745

m-dPEG^®₄-MAL

• Sinonimo/i: Polyethylene glycol
• Formula empirica (notazione di Hill): C₁₆H₂₆N₂O₇
• Numero CAS: 1263044-81-0
• Peso molecolare: 358.39
• Numero MDL: MFCD13185020
• Codice UNSPSC: 51171641
• ID PubChem: 329823946
• NACRES: NA.22

Proprietà

• Saggio: >90%
• Stato: solid or viscous liquid
• Impiego in reazioni chimiche: reactivity: thiol reactive; reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive
• Architettura del polimero: shape: linear; functionality: monofunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C1C=CC(N1CCC(NCCOCCOCCOCCOC)=O)=O
• InChI: DOHTYEHHGXSUJO-UHFFFAOYSA-N

Descrizione

Caratteristiche e vantaggi

The m-dPEG^®₄-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₄-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Note legali

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable