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G6600

Sigma-Aldrich

Glycine methyl ester hydrochloride

99%, for peptide synthesis

Sinonimo/i:

Glycine methyl ester·HCl, Methyl glycinate hydrochloride

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About This Item

Formula condensata:
NH2CH2COOCH3 · HCl
Numero CAS:
5680-79-5
Peso molecolare:
125.55
Beilstein:
3593644
Numero CE:
227-139-1
Numero MDL:
MFCD00012870
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
24895262
NACRES:
NA.22

product name

Glycine methyl ester hydrochloride, 99%

Saggio

99%

Forma fisica

powder, crystals or chunks

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Colore

white

Punto di fusione

175 °C (dec.) (lit.)

applicazioni

peptide synthesis

Stringa SMILE

Cl.COC(=O)CN

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H
COQRGFWWJBEXRC-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Glycine methyl ester hydrochloride, also known as methyl glycinate hydrochloride, is a derivative of glycine, used in the preparation of amino acids and organic compounds.

Applicazioni

Glycine methyl ester hydrochloride is used to synthesize cyclophosphazene compounds with amino acid esters as side groups. Additionally, it can be utilized to synthesize peptides in aqueous medium, which makes it a green method for peptide formation.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Akihiko Tohri et al.
European journal of biochemistry, 271(5), 962-971 (2004-03-11)
To elucidate the domains on the extrinsic 23 kDa protein involved in electrostatic interaction with the extrinsic 33 kDa protein in spinach photosystem II, we modified amino or carboxyl groups of the 23 kDa protein to uncharged methyl ester groups
Wenzhong Gao et al.
Organic letters, 7(19), 4241-4244 (2005-09-09)
[reaction: see text] A novel Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with acrylates has been developed. Up to 98/2 exo/endo selectivity and up to 98% enantiomeric excess have been achieved.
Glycine enolates: the large effect of iminium ion formation on alpha-amino carbon acidity.
A Rios et al.
Journal of the American Chemical Society, 123(32), 7949-7950 (2001-08-09)
L P Roguin et al.
The Biochemical journal, 224(2), 535-540 (1984-12-01)
Bovine somatotropin with an increasing number of its carboxylate groups modified by reaction with glycine methyl ester in the presence of a water-soluble carbodi-imide was tested for its activity in different bioassays. Only those derivatives which were known to be
J M Delfino et al.
International journal of peptide and protein research, 21(4), 440-450 (1983-04-01)
The reactivity of the carboxyl groups in bovine growth hormone was studied by reaction with 1-ethyl-3(3-dimethylaminopropyl) carbodiimide in the presence of an excess of glycinemethylester. Localization in the molecule of the various kinetically distinguishable carboxyl groups was achieved. Highest reactivity
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