CDE-509

Diether Liposomes

14:0 Diether PC:Cholesterol (70:30 molar ratio 1mM)

• Codice UNSPSC: 12352211
• NACRES: NA.25

Proprietà

• Livello qualitativo: 100
• Composizione: Phosphate buffered saline
• Concentrazione: 1 mM
• Impurezze: 30 mol % Cholesterol; 70 mol % 14:0 Diether PC
• Dimensione particelle: 100 nm
• pH: 7.4

Descrizione

Descrizione generale

Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. Ether lipids are a unique class of glycerophospholipids that have an alkyl chain attached to the sn-1 position by an ether bond.

Due to distinctive properties of ether lipids, liposomes made from ether lipids exhibit very unique characters and performance:
*ether bonds are more stable than ester linkages over a wide range of acidic or alkaline pH
*stability properties of the liposomes are enhanced by biopolar lipids and the saturated alkyl chains gives stability towards degradation in oxidative conditions
*the unusual stereochemistry of the glycerol backbone enhances the resistance against phopholipases

Due to their increased stability properties, ether liposomes are suitable candates for experiments that require an extended period of time as they can neither be hydrolyzed, oxidized, and can withstand higher temperatures.

Applicazioni

Drug delivery
Lipid-protein interactions

Stoccaggio e stabilità

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

Note legali

Cellsome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

Esclusione di responsabilità

For research use only

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable