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Documenti fondamentali

901950

Sigma-Aldrich

Alginate-RGD bioink

suitable for 3D bioprinting applications

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About This Item

Codice UNSPSC:
12352201
NACRES:
NA.23

Stato

viscous liquid

Impurezze

<25 EU/mL Endotoxin

Colore

white

pH

6.5-7

Densità

1.050 g/mL

applicazioni

3D bioprinting

Temperatura di conservazione

2-8°C

Descrizione generale

3D bioprinting is the printing of biocompatible materials, cells, growth factors, and the other supporting materials necessary to yield functional complex living tissues. 3D bioprinting has been used to generate several different types of tissue such as skin, bone, vascular grafts, and cartilage structures. Based upon the desired properties, different materials and formulations can be used to generate both hard and soft tissues. While several 3D printing methods exist, due to the sensitivity of the materials used, extrusion-based methods with bioinks are most commonly employed.

Material comes prepackaged in syringe with 5ml of product.
Alginate-RGD bioink, a natural biopolymer, is a biocompatible polysaccharide extracted from brown algae and modified with RGD peptide sequence by binding with peptide carboxylic acid functional group through carbodiimide chemistry.

Applicazioni

Alginate-RGD bioink has mild gelling characteristics at room temperature that makes it useful in the encapsulation of cells. It can be used in the formation of hydrogel-based bioink for the production of tissue-mimetic 3-D structures.
Due to its low cost, biocompatibility, and facile gelation, alginate is one of the most common components of commercial bioinks. Alginate is a naturally-occurring polysaccharide, obtained from the cell walls of brown algae, that is composed of guluronic and mannuronic acid. Alginate has been shown to readily form hydrogels under mild conditions and Arg-Gly-Asp (RGD) motifs have been added to improve cell adhesion after printing. Alginate-RGD acellular bioink is provided as a ready-to-print, low endotoxin, and aseptic formulation in 5 mL syringes.

Note legali

Product of Cellink

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCH0501

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Articoli

3D Bioprinting: Bioink Selection Guide

Bioinks selection guide for 3D bioprinting of cells for tissues engineering applications.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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