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808628

Sigma-Aldrich

Gold nanoparticles

5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O

Sinonimo/i:

Biotin Gold

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About This Item

Numero CE:
231-791-2
Codice UNSPSC:
12141717
NACRES:
NA.23

Materiali

PEG 5000

Livello qualitativo

100

Forma fisica

dispersion in H2O
nanoparticles

Confezionamento

pkg of 0.5 mL

OD

50

Area superficiale

6.18 m2/g

Diametro

5 nm

pH

5-7

Densità

1.00 g/cm3

λmax

513-517 nm

Gruppo funzionale

biotin

Temperatura di conservazione

2-8°C

InChI

1S/Au
PCHJSUWPFVWCPO-UHFFFAOYSA-N

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Descrizione generale

Gold nanoparticles PEG 5000 biotin terminated.

Applicazioni

Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent, and ranges from 515-520 nm for a 5 nm particle to 572 nm for a 100 nm particle.
Gold nanoparticles 5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Gold nanoparticles

Motao Zhu et al.
ACS nano, 14(3), 3703-3717 (2020-02-15)
Engineered nanoparticles could trigger inflammatory responses and potentiate a desired innate immune response for efficient immunotherapy. Here we report size-dependent activation of innate immune signaling pathways by gold (Au) nanoparticles. The ultrasmall-size (<10 nm) Au nanoparticles preferentially activate the NLRP3
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Heo DN, et al.
Biomaterials, 33(3), 856-866 (2012)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Itani R, et al.
Theranostics, 10(13), 5932-5932 (2020)
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)

Articoli

2D Materials Matter: A Perspective on Biosensing Applications

Professor Ebrahimi and Professor Robinson (Pennsylvania State University, USA) summarize recent advances in the synthesis of these 2D materials, resulting material properties, and related applications in biosensing of neurotransmitters, metabolites, proteins, nucleic acids, bacterial cells, and heavy metals.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.