762229

tBuXPhos Pd G3

98%

• Sinonimo/i: tBuXPhos-Pd-G3, [(2-Di-tert-butylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′-biphenyl)] palladium(II) methanesulfonate
• Formula empirica (notazione di Hill): C₄₂H₅₈NO₃PPdS
• Numero CAS: 1447963-75-8
• Peso molecolare: 794.37
• Numero MDL: MFCD22666411
• Codice UNSPSC: 12161600
• ID PubChem: 329766956
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: 98%
• Forma fisica: solid
• Caratteristiche: generation 3
• Impiego in reazioni chimiche: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings
• Punto di fusione: 130-140 °C
• Gruppo funzionale: phosphine
• Stringa SMILE: CS(=O)(=O)O[Pd]c1ccccc1-c2ccccc2N.CC(C)c3cc(C(C)C)c(c(c3)C(C)C)-c4ccccc4P(C(C)(C)C)C(C)(C)C
• InChI: 1S/C29H45P.C12H10N.CH4O3S.Pd/c1-19(2)22-17-24(20(3)4)27(25(18-22)21(5)6)23-15-13-14-16-26(23)30(28(7,8)9)29(10,11)12;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h13-21H,1-12H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1; SQQOHCLJPLSJGX-UHFFFAOYSA-M

Descrizione

Descrizione generale

tBuXPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. tBuXPhos Pd G3 is an excellent reagent for Buchwald-Hartwig cross-coupling reaction. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Applicazioni

tBuXPhos Pd G3 may be used to synthesize 4-cyano-7-azaindole from 4-chloro-7-azaindole by cyanation reaction. It may also be used for the α-arylation reaction of acetate esters at room temperature.

For small scale and high throughput uses, product is also available as ChemBeads (931055)

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable