663190

Ethyl 5-methylindole-2-carboxylate

97%

• Sinonimo/i: 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• Formula empirica (notazione di Hill): C₁₂H₁₃NO₂
• Numero CAS: 16382-15-3
• Peso molecolare: 203.24
• Numero MDL: MFCD00022703
• Codice UNSPSC: 12352100
• ID PubChem: 24884618
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: 97%
• Forma fisica: solid
• Punto di fusione: 160-164 °C
• Gruppo funzionale: ester
• Stringa SMILE: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3; KMVFKXFOPNKHEM-UHFFFAOYSA-N

Descrizione

Descrizione generale

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.

Applicazioni

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)