254916
7,8-Dihydroxy-6-methoxycoumarin
98%
Sinonimo/i:
Fraxetin
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About This Item
Formula empirica (notazione di Hill):
C10H8O5
Numero CAS:
Peso molecolare:
208.17
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23
Prodotti consigliati
Livello qualitativo
Saggio
98%
Stato
powder
Punto di fusione
230-231 °C (lit.)
Stringa SMILE
COc1cc2C=CC(=O)Oc2c(O)c1O
InChI
1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
HAVWRBANWNTOJX-UHFFFAOYSA-N
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Descrizione generale
7,8-Dihydroxy-6-methoxycoumarin is a versatile compound known for its unique fluorescence properties and its role as a photoinitiator in polymerization processes. It exhibits high reactivity under UV light, making it an ideal candidate for applications in the polymerization industry, particularly in the formulation of coatings, adhesives, and inks. It is also used in biomedical applications, such as drug delivery due to its biocompatibility.
Applicazioni
7,8-Dihydroxy-6-methoxycoumarincan be used as a UV absorber in polymer formulations. Its ability to absorbultraviolet light helps in protecting polymers from degradation caused by UVradiation, thereby improving their longevity and stability.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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María Francisca Molina-Jiménez et al.
Brain research, 1009(1-2), 9-16 (2004-05-04)
Rotenone-induced apoptosis is considered to contribute to the etiology of Parkinson's disease (PD). We try to prevent the apoptosis induced by rotenone toxicity with 50 microM myricetin, 100 microM fraxetin and 100 microM N-acetylcysteine (NAC) that protect against reactive oxygen
Po-Lin Kuo et al.
Biological & pharmaceutical bulletin, 29(1), 119-124 (2006-01-06)
Fraxetin (7,8-dihydroxy-6-methoxy coumarin), a coumarin derivative, was investigated for its effects on differentiation of osteoblasts. By means of alkaline phosphatase (ALP) activity and osteocalcin ELISA assay, we have shown that fraxetin exhibits a significant induction of differentiation in two human
Francesco Epifano et al.
Mini reviews in medicinal chemistry, 9(11), 1262-1271 (2009-11-26)
Neurodegenerative disorders are a heterogeneous group of diseases and are among the most invaliding syndromes for humans. The aim of this manuscript is to review what has been reported so far in the literature about coumarins as a novel class
María Francisca Molina-Jiménez et al.
Toxicology and applied pharmacology, 209(3), 214-225 (2005-05-21)
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Recently, it has been shown that fraxetin (coumarin) and myricetin (flavonoid) have significant neuroprotective effects against apoptosis induced by rotenone, increase the total glutathione levels in
Phuong Thien Thuong et al.
Biological & pharmaceutical bulletin, 32(9), 1527-1532 (2009-09-02)
Atherosclerosis is main cause of arteriosclerosis. The pivotal role of low-density lipoprotein (LDL) oxidation in atherogenesis suggests antioxidants may help prevent cardiovascular disease. Fraxinus rhynchophylla DENCE (Oleaceae) is a traditional medicinal plant from East Asia. During the course of characterizing
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