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Merck
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Documenti fondamentali

217719

Sigma-Aldrich

4-Amino-2-chlorobenzoic acid

97%

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About This Item

Formula condensata:
H2NC6H3(Cl)CO2H
Numero CAS:
Peso molecolare:
171.58
Beilstein:
2803668
Numero CE:
Numero MDL:
Codice UNSPSC:
12352106
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

97%

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

211 °C (dec.) (lit.)

applicazioni

peptide synthesis

Stringa SMILE

Nc1ccc(C(O)=O)c(Cl)c1

InChI

1S/C7H6ClNO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,9H2,(H,10,11)
MBDUKNCPOPMRJQ-UHFFFAOYSA-N

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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E H Philipson et al.
American journal of obstetrics and gynecology, 151(3), 322-324 (1985-02-01)
Amide-linked local anesthetic agents, such as lidocaine and bupivacaine, can become "trapped" in their ionized forms on the fetal side of the placenta, and therefore their net transfer across the placenta is increased. An ester-linked local anesthetic agent, 2-chloroprocaine, is
B R Kuhnert et al.
Anesthesia and analgesia, 62(12), 1089-1094 (1983-12-01)
Little is known about the pharmacology of the metabolites of 2-chloroprocaine in obstetrical patients. The primary objective of this study was to describe the elimination of 2-chloroaminobenzoic acid (CABA) in maternal and neonatal urine after epidural anesthesia. A secondary objective
R R Weiss et al.
Anesthesia and analgesia, 62(2), 168-173 (1983-02-01)
2-Chloroprocaine (CP) has recently been recommended as a less toxic alternative to amide-type local anesthetics due to its rapid metabolism. A double-blind, randomized study comparing CP to lidocaine when used for paracervical block was carried out. Twenty-nine patients received CP
K Krohg et al.
Anesthesiology, 54(4), 329-332 (1981-04-01)
The purpose of this study was to identify the metabolic pathway of 2-chloro-4-aminobenzoic acid (CABA), a primary metabolite of chloroprocaine. Urine was collected from 4 healthy, pregnant women following the epidural administration of 600 mg chloroprocaine. The urinary metabolites were
P K Janicki et al.
Journal of chromatography. B, Biomedical applications, 675(2), 336-341 (1996-01-26)
A sensitive and specific high-performance liquid chromatographic method for determination of the 2-chloroprocaine, local anesthetic of ester type, and its major metabolite 2-chloroaminobenzoic acid, has been developed and validated. A single-step extraction procedure is employed followed by high-performance liquid chromatographic

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