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13900

Sigma-Aldrich

O-Benzyl-L-serine

≥99.0% (NT)

Sinonimo/i:

(S)-2-Amino-3-benzyloxypropionic acid

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About This Item

Formula empirica (notazione di Hill):
C10H13NO3
Numero CAS:
4726-96-9
Peso molecolare:
195.22
Beilstein:
2114846
Numero CE:
225-220-6
Numero MDL:
MFCD00065937
Codice UNSPSC:
12352200
ID PubChem:
57647117
NACRES:
NA.22

Saggio

≥99.0% (NT)

Forma fisica

powder

Attività ottica

[α]20/D +21±2°, c = 2% in acetic acid: water (4:1) (+ 1 Eq HCl)

Purezza ottica

enantiomeric ratio: ≥99.5:0.5 (TLC)

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

~227 °C (dec.)

applicazioni

peptide synthesis

Stringa SMILE

N[C@@H](COCc1ccccc1)C(O)=O

InChI

1S/C10H13NO3/c11-9(10(12)13)7-14-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1
IDGQXGPQOGUGIX-VIFPVBQESA-N

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Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCBR5325V
1325275
1325275V
1325275
1183329

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N-Methyl-D-aspartic acid ≥98% (TLC), solid

Sigma-Aldrich

M3262

N-Methyl-D-aspartic acid

Amir H Ghassemi et al.
Pharmaceutical research, 29(1), 110-120 (2011-07-12)
To investigate the in vitro release of octreotide acetate, a somatostatin agonist, from microspheres based on a hydrophilic polyester, poly(D,L-lactide-co-hydroxymethyl glycolide) (PLHMGA). Spherical and non-porous octreotide-loaded PLHMGA microspheres (12 to 16 μm) and loading efficiency of 60-70% were prepared by a
Amir H Ghassemi et al.
Pharmaceutical research, 27(9), 2008-2017 (2010-07-06)
To study the release of a model protein, bovine serum albumin (BSA), from microspheres of an hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid) (PLHMGA). BSA-loaded microspheres were prepared by a double emulsion solvent evaporation method. The effect of copolymer composition and
Roman V Uzhachenko et al.
Cell reports, 35(1), 108944-108944 (2021-04-08)
Inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6i) delay progression of metastatic breast cancer. However, complete responses are uncommon and tumors eventually relapse. Here, we show that CDK4/6i can enhance efficacy of T cell-based therapies, such as adoptive T cell transfer or
Neda Samadi et al.
Pharmaceutical research, 31(10), 2593-2604 (2014-03-15)
To investigate the effect of polyethylene glycol (PEG) in nanoparticles based on blends of hydroxylated aliphatic polyester, poly(D,L-lactic-co-glycolic-co-hydroxymethyl glycolic acid) (PLGHMGA) and PEG-PLGHMGA block copolymers on their degradation and release behavior. Protein-loaded nanoparticles were prepared with blends of varying ratios
F Kazazi-Hyseni et al.
International journal of pharmaceutics, 482(1-2), 99-109 (2014-12-17)
Poly(D,L-lactic-co-hydroxymethyl glycolic acid) (PLHMGA) is a biodegradable copolymer with potential as a novel carrier in polymeric drug delivery systems. In this study, the biocompatibility of PLHMGA microspheres (PLHMGA-ms) was investigated both in vitro in three different cell types (PK-84, HK-2

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