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Key Documents

122505

Sigma-Aldrich

2,3-Dihydroxypyridine

95%

Sinonimo/i:

2,3-Pyridinediol

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About This Item

Formula empirica (notazione di Hill):
C5H5NO2
Numero CAS:
Peso molecolare:
111.10
Beilstein:
109848
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

95%

Punto di fusione

245 °C (dec.) (lit.)

Stringa SMILE

Oc1cccnc1O

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)
GGOZGYRTNQBSSA-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

2,3-Dihydroxypyridine(DHP) was used in the synthesis of DHP loaded amberlite XAD-2 via azo coupler. It was used in the synthesis of new macromolecular chelators by loading DHP on cellulose via linkers -NH-CH2-CH2-NH-SO2-C6H4-N=N- and -SO2-C6H4-N=N.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Certificati d'analisi (COA)

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2, 3-Dihydroxypyridine loaded amberlite XAD-2 (AXAD-2-DHP): preparation, sorption-desorption equilibria with metal ions, and applications in quantitative metal ion enrichment from water, milk and vitamin samples.
Venkatesh G, et al.
Microchimica Acta, 149(3-4), 213-221 (2005)
Lei Wang et al.
European journal of medicinal chemistry, 156, 680-691 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl
Jayakanth Kankanala et al.
European journal of medicinal chemistry, 141, 149-161 (2017-10-17)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral
Vibha Gurnani et al.
Analytical and bioanalytical chemistry, 377(6), 1079-1086 (2003-08-09)
New macromolecular chelators have been synthesized, by loading 2,3-dihydroxypyridine (DHP) on cellulose via linkers -NH-CH(2)-CH(2)-NH-SO(2)-C(6)H(4)-N=N- and -SO(2)-C(6)H(4)-N=N-, and characterized by elemental analysis, TGA, IR, and CPMAS (13)C NMR spectra. The cellulose with DHP anchored by the shorter linker had better
Elham Y Hashem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 58(2), 239-247 (2002-01-26)
The electronic absorption spectra of some substituted pyridinols in organic solvents of different polarities are studied. Also, the solvent effects on the intramolecular charge transfer bands are discussed using various solvent parameters. The acid-base equilibria of the compounds used are

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