Passa al contenuto
Merck

SELPLG

selectin P ligand

Sinonimi:
CD162, CLA, PSGL-1, PSGL1
Specie:
ID UniProtKB:
ID gene:
  • Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(20345) selectin, platelet (p-selectin) ligand
  • Rat(363930) selectin P ligand
  • cow(617434) selectin P ligand
  • sheep(101102589) selectin P ligand
  • naked mole-rat(101713908) selectin P ligand
  • domestic guinea pig(100712957) selectin P ligand
  • Zebrafish(100884146) selectin P ligand
  • chicken(772212) selectin P ligand
  • dog(611673) selectin P ligand
  • Horse(100034025) selectin P ligand
  • domestic cat(101087945) selectin P ligand

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

N° Catalogo
Descrizione
Specie
Human PSGL-1 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PSGL-1/CD162 Antibody, clone KPL-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-P-Selectin Glycoprotein Ligand-1 Antibody, clone KPL-1, clone KPL-1, Chemicon®, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PSGL-1/CD162 Antibody, clone HECA-452, ,
Reattività con
human
Applicazione
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-CD162-APC antibody produced in mouse, clone TC2,
Reattività con
Applicazione
flow cytometry
Anti-SELPLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human SELPLG,
Specie
human
MISSION® esiRNA, targeting mouse Selplg,
Specie
mouse