Passa al contenuto
Merck

SCN2A

sodium channel, voltage-gated, type II, alpha subunit

Sinonimi:
BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2
Specie:
ID UniProtKB:
ID gene:
  • Human(6326) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • chicken(395945) sodium channel, voltage-gated, type II, alpha subunit
  • dog(478773) sodium channel, voltage-gated, type II, alpha subunit
  • Horse(100051816) sodium channel, voltage-gated, type II, alpha subunit
  • domestic cat(101080472) sodium channel, voltage-gated, type II, alpha subunit
  • domestic guinea pig(100716680) sodium channel, voltage-gated, type II, alpha subunit
  • naked mole-rat(101715020) sodium channel, voltage-gated, type II, alpha subunit
  • cow(539718) sodium channel, voltage-gated, type II, alpha subunit
  • sheep(101103126) sodium channel, voltage-gated, type II, alpha subunit

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Riluzole, solid,
Specie
rat, human
Oxcarbazepine, ≥98% (HPLC), solid,
Specie
rat, human
BIA 2-093, ≥98% (HPLC), solid,
Specie
rat, human
Lidocaine, powder,
Specie
rat, human
Lamotrigine, ≥98%, powder,
Specie
rat, human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-SCN2A Antibody, clone 5H10.2, clone 5H10.2, from mouse,
Reattività con
human
Applicazione
western blot
Anti-SODIUM CHANNEL-PAN antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type II, Chemicon®, from rabbit,
Reattività con
mouse, rat
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Reattività con
mammals
Applicazione
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Lidocaine hydrochloride monohydrate, solid,
Specie
human
Procaine hydrochloride, ≥97%,
Specie
human
Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Lidocaine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Procainamide hydrochloride, ≥98% (HPLC),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Scn2a,
Specie
mouse
MISSION® esiRNA, targeting human SCN2A,
Specie
human