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Merck

PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Sinonimi:
COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Specie:
ID UniProtKB:
ID gene:
  • Human(5742) Summary: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
  • Mouse(19224) prostaglandin-endoperoxide synthase 1
  • Rat(24693) prostaglandin-endoperoxide synthase 1
  • Zebrafish(246226) prostaglandin-endoperoxide synthase 1
  • dog(403544) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(100034087) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(101092557) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(427752) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100714030) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101698854) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282022) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443551) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Anti-PTGS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-COX1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot
Anti-COX1/PTGS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PTGS1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, guinea pig, horse, human, mouse, rat, sheep
Applicazione
immunohistochemistry
western blot
Anti-PTGS1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Niflumic acid, ,
Specie
human
Antipyrine, analytical standard,
Specie
human
Antipyrine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Phenazone, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Diclofenac, ,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PTGS1,
Specie
human
MISSION® esiRNA, targeting mouse Ptgs1,
Specie
mouse