Passa al contenuto
Merck

PTGER4

prostaglandin E receptor 4 (subtype EP4)

Sinonimi:
EP4, EP4R
Specie:
ID UniProtKB:
ID gene:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Dinoprostone, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Dinoprostone, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Prostaglandin E1, ≥98% (HPLC), synthetic,
Specie
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Specie
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Specie
human, mouse

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Prostaglandin E1, ≥98% (HPLC), synthetic,
Specie
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Specie
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Specie
human, mouse
Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture,
Specie
human, mouse
Prostaglandin E2, ≥93% (HPLC), synthetic,
Specie
mouse, human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PTGER4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-EP4 Prostaglandin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human
Applicazione
ELISA
western blot
Anti-PE2R4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
Prostaglandin E2, ≥93% (HPLC), synthetic,
Specie
mouse, human
Indomethacin, 98.5-100.5% (in accordance with EP),
Specie
human, mouse, rat

Proteins

N° Catalogo
Descrizione
Specie
ChemiScreen Membrane Preparation
Recombinant Human EP4 Prostanoid Receptor
, Human EP4 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PTGER4,
Specie
human
MISSION® esiRNA, targeting mouse Ptger4,
Specie
mouse